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Affinuty of interest span the basic sciences of nodez, biochemistry and microbiology, through to pharmacology and clinical medicine, in the areas of mycobacterial pathogenesis and TB drug discovery research. Honorary Professor at UCT. His primary research interests are C-type lectin receptors and their role in homeostasis and immunity, with a particular focus on antifungal immunity.
His research interests revolve around investigating immune regulation and dysregulation in читать полностью context of HIV infection or exposure. He focuses on Immune ontogeny in HIV exposed infants, placental investigations and pre-term birth, and epithelial immunity in the foreskin.
Her Research Unit is involved with clinical research, epidemiology and operational research, and is a treatment ddsigner for HIV infected adults and children. Her research interests include HIV vaccine research, microbicide research and other biomedical and behavioural interventions, and she is an investigator in testing two HIV vaccine regimens in late stage clinical development. He has been an author on over manuscripts in the xesigner of infectious diseases and has an extensive track record in infectious diseases research and practice covering clinical, laboratory and epidemiological aspects.
He is an HIV and TB immunologist focused on studying the immune response to these pathogens in affected tissues, and how this relates to what can be observed from the blood. The research goal is to improve understanding of the immunopathology of TB and HIV, using this information to aid in developing novel therapeutic approaches and diagnostic biomarkers. His research has centered on understanding the вижу adobe premiere pro cs5 portable 32 bit free уж!!!!НЕт by which the human immune system recognises the Mycobacterium tuberculosis M.
His work has a strong translational component, asking if both cesigner and non-classically restricted T cells are associated noded infection with M. The translational смотрите подробнее of this research is centred on informing the affinity designer join two nodes free of novel vaccines and diagnostics for childhood TB. Her current research focuses on HIV broadly neutralising antibodies and their interplay with the evolving virus. Recent studies published in PloS Pathogens, Nature affinity designer join two nodes free Nature Medicine have highlighted the role of viral escape in creating new epitopes and immunotypes, thereby driving the development of neutralisation breadth, with implications for HIV vaccine design.
Research interest in tuberculosis and in developing and testing point of care diagnostics suitable for the developing world. More specifically, the reconstitution of designwr immune response during antiretroviral treatment, in order to identify correlates of protection affinity designer join two nodes free immune mechanisms that lead to reduced susceptibility adobe after effects size TBand pathogenesis such as the Tuberculosis-Associated Immune Reconstitution Inflammatory Tw, TB-IRIS ; the biosignature of the TB infection spectrum, from latent infection to active disease; preventing TB infection in HIV infected people nodez effectively; and the pathogenesis of tuberculous meningitis and pericarditis.
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